Although the COVID-19 pandemic is no longer classified as a global emergency, the virus hasn’t disappeared — it has evolved. In September 2025, several COVID-19 variants continue to circulate globally, with differing levels of severity and transmission potential. As public tracking systems adapt post-pandemic, many are left wondering: which variants are active now, and do we still need to worry?

According to infectious disease experts, including Dr. Mark Rupp, the most frequently identified variants in early 2025 are offshoots of the Omicron lineage — notably JN.1 and BA.2.86 subvariants, both of which have shown increased transmissibility. These strains are not necessarily more dangerous but have adaptations that help them bypass previous immunity, including from past infection or vaccination.

Why Variant Tracking Is More Difficult Now

Since the U.S. ended its Public Health Emergency (PHE) on May 11, 2023, aggregate COVID-19 case and death reporting has significantly declined. Fewer people are getting lab-based tests, and home testing kits — which aren’t always reported — have become the norm. This means actual case numbers and variant spread may be underestimated.

What the Data Shows in September 2025

Based on the latest CDC indicators:

• Emergency room visits related to COVID-19 have dropped 12.2% in the most recent week.
• Only 0.6% of ER visits are currently attributed to COVID-19.
• The test positivity rate as of April 5 was 3.6%, which is below the 5% threshold for uncontrolled transmission.

These numbers suggest manageable levels of community spread, but caution remains due to reporting gaps and underdiagnosis.

Are New Variants More Severe?

So far, current strains have not shown increased severity compared to previous waves. Most hospitalizations involve unvaccinated individuals, the elderly, or those with chronic conditions. The symptoms — sore throat, mild fever, congestion, fatigue — are often less severe than earlier pandemic variants but still disruptive, especially in vulnerable groups.

Vaccine and Booster Updates

Updated vaccines tailored for current Omicron subvariants have been recommended for high-risk groups. Although uptake is lower than in previous years, those receiving boosters tend to experience milder symptoms and shorter illness duration.

COVID-19 is no longer the emergency it once was — but that doesn’t mean it’s gone. Variants will continue to evolve, and seasonal surges are still possible. Keeping an eye on local trends, staying updated on booster recommendations, and practicing smart hygiene habits remain key tools in protecting yourself and those around you.